DUBLIN-(BUSINESS WIRE)-Research and Markets(http:/www.researchandmarkets.com/research/77bfe1/influenza_vaccine) has announced the addition of Decision Resources, Inc.'s new report "Influenza Vaccine Manufacturing: Can New Technologies Open the Production Bottleneck?" to (…)
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[Source: Business Wire]
COPENHAGEN, Denmark-(BUSINESS WIRE)-H. Lundbeck A/S (Lundbeck) announced today that the U.S. Federal District Court has ruled in favor of Lundbeck and found no violation of the antitrust laws in the Company s acquisition of NeoProfen (ibuprofen lysine) Injection (10mg/mL), a (…)
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[Source: Business Wire]
PARP-1 inhibitors have emerged as a promising therapeutic class of compounds, and numerous PARP inhibitors, including iniparib (BiPar Sciences Inc/sanofi-aventis), olaparib (AstraZeneca plc), veliparib (Abbott Laboratories), PF-1367338 (Pfizer Inc), MK-4827 (Merck & Co Inc) and (…)
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[Source: NCBI PubMed]
Genistein and 5-hydroxyindole (5-HI) potentiate the alpha7 nicotinic acetylcholine receptor current by primarily increasing peak amplitude, a property of type I alpha7 positive allosteric modulation. In this study, the effects of these two compounds were investigated at two (…)
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[Source: NCBI PubMed]
BACKGROUND: The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. METHODS: We enrolled in our study 10,744 overweight or obese subjects, 55 years of age (…)
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[Source: NCBI PubMed]
In recent decades the population of both elderly men and women has grown substantially worldwide. Aging is associated with a number of pathologies involving various organs including the skeleton. Age-related bone loss and resultant osteoporosis put the elderly population at an (…)
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[Source: NCBI PubMed]
This retrospective study linking two databases shows that both black and Hispanic living kidney donors had a higher relative risk of hypertension, drug-treated diabetes mellitus, and chronic kidney disease after donation than did white donors, similar to the risks in the (…)
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[Source: NCBI PubMed]
This Letter describes the lead discovery, optimization, and biological characterization of a series of substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as potent inhibitors of IGF1R, EGFR, and ErbB2. The leading compound 11 showed an IGF1R IC(50) of 12nM, an EGFR (L858R) (…)
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[Source: NCBI PubMed]
Glycan structures on glycoproteins are controlled by several factors such as regulated expression of glycosyltransferases and glycosylhydrolases, as well as regulation of glycoprotein expression, folding, and transport through the ER and Golgi. In cancer, for example, the (…)
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[Source: NCBI PubMed]
BACKGROUND: The health care debate in the United States centers on a concept that is fundamental to any service-based profession yet minimally integrated into the health care community: value creation. Value in health care has been defined as outcome achieved per dollar spent, (…)
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[Source: NCBI PubMed]
In recent years immunotherapy-based approaches to treat Alzheimer's disease have become the subject of intensive research. However, an important mechanistic-related safety concern is exacerbation of the risk of microhemorrhage that may be associated with fast removal of (…)
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[Source: NCBI PubMed]
OBJECTIVE: Having developed and validated a disease-specific health-related quality of life (HRQOL) measure for patients with systemic lupus erythematosus (SLE), the LupusQoL, we determined its relationship to demographic and clinical measurements in a group of patients with (…)
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[Source: NCBI PubMed]
Bloomberg - John Lamb, a retired auto mechanic in New Zealand, was the first patient to get one of Abbott Laboratories experimental heart stents to treat chest pains. In a sense, he now has nothing to show for it - as doctors intended all along.
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[Source: BioSpace]
09.09.2010 - Pevion Biotech AG announced the appointment of Evert Kueppers as its new Chief Executive Officer, succeeding Thomas Stauffer. Prior to joining Pevion, Evert Kueppers was CEO of Pieris AG, a Munich-based biotechnology company, which he successfully restructured and (…)
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[Source: Bionity.com]
ROCKVILLE, Md.-(BUSINESS WIRE)-Emergent BioSolutions Inc. (NYSE:EBS) announced today that the U.S. Department of Justice and Federal Trade Commission granted early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 ("HSR Act"), as (…)
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[Source: Business Wire]
Novel theoretical frameworks place the symptom profile of generalised anxiety disorder (GAD) within the context of dysfunctional emotional processes. It is suggested that fear and intolerance of emotions exacerbate subjective distress and motivate the use of maladaptive coping (…)
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[Source: NCBI PubMed]
Schizophrenia is a highly familial, neurodevelopmental disorder that is associated with several neuropsychiatric, psychological, and neuropathological features. Whilst pharmacological animal models of dopaminergic and glutamatergic dysfunction have helped advance our (…)
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[Source: NCBI PubMed]
OBJECTIVE: To determine the values of PSA in Spanish workers without history of prostate problems and compare them with other geographical latitudes. METHODS: Observational, retrospective, multicenter and population-based study, conducted between January 1 and December 31, (…)
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[Source: NCBI PubMed]
OBJECTIVE: Previous studies have shown that patients with schizophrenia have less modulation of the task-positive and default mode neural networks during novelty detection. The diminished modulation may be interpreted as less functional activation of the task-positive network (…)
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[Source: NCBI PubMed]
Sodium polystyrene sulfonate (SPS) potassium binding resins increase colonic potassium excretion and are approved by the U.S. Food and Drug Administration (FDA) for the treatment of hyperkalemia. In 2009, the FDA recommended that sorbitol, a cathartic often given with SPS to (…)
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[Source: NCBI PubMed]
OBJECTIVE: To create a computer-based model for employers to better understand the burden of coronary heart disease (CHD) to their organizations. METHODS: A user-friendly model was developed to allow employers to evaluate the burden of CHD. Inputs include the demographic (…)
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[Source: NCBI PubMed]
This study was performed to prepare high-dose Nicotinic Acid (NA) loaded sustained-release pellets coated with double polymer and simvastatin (SIM). The uncoated pellets were prepared by extrusion-spheronization and the double ethylcellucose (EC) films were coated in a (…)
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[Source: NCBI PubMed]
Patterns of HIV-1 protease inhibitor (PI) resistance-associated mutations and effects on PI susceptibility associated with the L76V mutation were studied in a large database. Of 20,501 sequences with /=1 PI RAM, 3.2% contained L76V; it was alone in 0.04%. Common partner (…)
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[Source: NCBI PubMed]
INTRODUCTION: Prostate cancer (PC) states as the most frequent tumor in elderly patients. Although no direct involvement in death-related, PC entails an important lost in patient's quality of life. There are several questionnaires adapted to Spanish in order to measure the (…)
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[Source: NCBI PubMed]
Neutrophil gelatinase-associated lipocalin (NGAL) is a promising new renal biomarker that can reduce the time to diagnose acute kidney injury (AKI). There is little information available about complex glycans on NGAL. Detailed structural characterization of NGAL is necessary to (…)
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[Source: NCBI PubMed]
PURPOSE: To study the perspectives and experiences of stroke survivors and partners of stroke survivors regarding sexual issues and perceived rehabilitation needs. METHODS: Using semi-structured interviews, 15 stroke survivors and 14 partners of stroke survivors (median age of (…)
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[Source: NCBI PubMed]
BACKGROUND: Generalized anxiety disorder (GAD) is a common disorder in older adults, which has been linked to hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis in this age group. The authors examined whether treatment of GAD in older adults with a selective (…)
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[Source: NCBI PubMed]
BERNE, Switzerland, September 7, 2010 /PRNewswire/ - Pevion Biotech AG announced today the appointment of Evert Kueppers as its new Chief Executive Officer, succeeding Thomas Stauffer. "We would like to thank Thomas for his excellent contributions over the years and wish him (…)
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[Source: BioSpace]
A new IFPMA study(1), announced at the "Options for the Control of Influenza VII" conference in Hong Kong, shows that global vaccine coverage remains uneven and low overall, despite total distribution of seasonal influenza vaccines nearly doubling over the last six years. The (…)
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[Source: Medical News Today]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/e3fec8/mens_health_thera) has announced the addition of the "Men's Health Therapeutics Market to 2016 - Selective Serotonin Reuptake Inhibitors, Hormone Replacement Therapy and (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/8cd614/global_coronary_st) has announced the addition of the "Global Coronary Stent Market Report: 2010 Edition" report to their offering. Global Coronary Stent Market Report: 2010 Edition (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/2fb050/abbott_india_limit) has announced the addition of the "Abbott India Limited-Detailed Product Pipeline" company profile to their offering. Abbott India Limited-Detailed Product (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/41867b/cancer_drug_resist) has announced the addition of the "Cancer Drug Resistance" report to their offering. Drug resistance is the single most important cause of cancer treatment (…)
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[Source: Business Wire]
06.09.2010 - During its first meeting, the Board of Directors of Pierre Fabre SA chaired by Mr. Pierre Fabre appointed Olivier Bohuon as the company's Chief Executive Officer. Olivier Bohuon, 51, has until now been the executive vice-president of Abbott Corporation and (…)
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[Source: Bionity.com]
NAARDEN, The Netherlands & MUNICH, Germany-(BUSINESS WIRE)-Forbion Capital Partners, a leading investment firm dedicated to the life science sector, today announces the final closings of both FCF I Co-Invest Fund and of FCF II, raising a total of more than ¬190m ($240m). (…)
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[Source: Business Wire]
New York Times - Abbott Laboratories has called a halt to the sale of its European flu-vaccine unit because of a dissapointing run of initial bids, The Wall Street Journal reported.
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[Source: BioSpace]
Berlin, Germany, and Seattle, WA, U.S.A., September 3, 2010 - Epigenomics AG (Frankfurt Prime Standard: ECX), a cancer molecular diagnostics company informed, that Geert W. Nygaard, CEO Epigenomics AG, will provide a corporate update at two upcoming Investor conferences in (…)
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[Source: BioSpace]
Abbott (NYSE: ABT) announced it has received approval from the U.S. Food and Drug Administration (FDA) to market the Abbott RealTime HBV assay for measuring viral load or the amount of hepatitis B virus (HBV) in a patient's blood. It is the first and only approved test capable (…)
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[Source: Medical News Today]
Siemens Healthcare Diagnostics announces Eric Olson's appointment as President of the IVD Industry Connectivity Consortium (IICC). Founded by the top worldwide in vitro diagnostics (IVD) manufacturers, IICC's mission is to create and ensure adoption of a unified connectivity (…)
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[Source: Medical News Today]
SAVANNAH, Ga.-(BUSINESS WIRE)-Health Discovery Corporation (OTCBB: HDVY) is pleased to announce that Herbert A. Fritsche, Ph.D., recently retired Professor of Laboratory Medicine and Chief of the Clinical Chemistry Section at The University of Texas, M.D. Anderson Cancer (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/886118/trends_in_generics) has announced the addition of the "Trends in Generics Industry Ownership: Evaluating Changing Industry Paradigms and Emerging Players" report to their offering. (…)
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[Source: Business Wire]
LONDON & GENEVA-(BUSINESS WIRE)-Index Ventures today announced that Dr Kevin Johnson has formally expanded his relationship with the firm and has joined the team as a Partner in the Life Sciences team. Dr Johnson will focus specifically on seeking out new assets in the (…)
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[Source: Business Wire]