PALO ALTO, Calif.-(BUSINESS WIRE)-Anacor Pharmaceuticals today announced the establishment of a research agreement with Eli Lilly and Company to create and develop new therapeutics for animal health. The collaboration takes advantage of Anacor s boron chemistry platform and (…)
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[Source: Business Wire]
Abstract Objective: To identify reasons for discontinuation and continuation of antipsychotic medications in the treatment of schizophrenia from the patients' and their clinicians' perspectives. Research design and methods: Two measures were previously developed to assess the (…)
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[Source: NCBI PubMed]
The incidence of treatment-emergent extrapyramidal symptoms (EPSs) and tardive dyskinesia (TD) in schizophrenic patients, and the clinical characteristics associated with an increased risk of developing EPSs and TD were examined. Patients (N = 7728) in the 3-year, prospective, (…)
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[Source: NCBI PubMed]
OBJECTIVE: To unravel the complex mechanisms of the sphingolipid de novo synthesis pathway by using the sphingomyelin (SM) synthase 2 (Sms2) gene knockout (KO) approach to test our hypothesis that selectively decreasing plasma lipoprotein SM can play an important role in (…)
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[Source: NCBI PubMed]
Bloomberg - Eli Lilly & Co. plans to invest as much as $150 million in three venture capital funds to aid development of new medicines, as the company faces generic competition next year to its top-selling antipsychotic drug.
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[Source: BioSpace]
PALO ALTO, Calif., Sep 09, 2010 (BUSINESS WIRE) - Anacor Pharmaceuticals today announced the establishment of a research agreement with Eli Lilly and Company to create and develop new therapeutics for animal health. The collaboration takes advantage of Anacor's boron chemistry (…)
[Read article]
[Source: BioSpace]
Abstract Objective: To examine and compare medication adherence and direct healthcare costs between duloxetine and pregabalin initiators among patients with fibromyalgia. Methods: A retrospective analysis of commercially insured fibromyalgia patients aged 18 to 64 was conducted (…)
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[Source: NCBI PubMed]
The European Neuroscience-Seventh Biennial FENS Forum, held in Amsterdam, included topics covering new therapeutic developments in the field of neuroscience. This conference report highlights selected presentations on sodium channel inhibitors, ionotropic glutamate receptor (…)
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[Source: NCBI PubMed]
Adherence to, and persistence with, treatments for osteoporosis are low. Adherence with teriparatide decreases over time. Higher copayments in the commercial/Medicare population were associated with worse persistence. Understanding factors such as prior screening, prior (…)
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[Source: NCBI PubMed]
In order to determine a threshold for nongenotoxic carcinogens, the traditional risk assessment approach has been to identify a mode of action (MOA) with a nonlinear dose-response. The dose-response for one or more key event(s) linked to the MOA for carcinogenicity allows a (…)
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[Source: NCBI PubMed]
BACKGROUND: Clopidogrel and prasugrel are subject to efflux via P-glycoprotein (encoded by ABCB1, also known as MDR1). ABCB1 polymorphisms, particularly 3435C- T, may affect drug transport and efficacy. We aimed to assess the effect of this polymorphism by itself and alongside (…)
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[Source: NCBI PubMed]
Senile plaques formed by beta-amyloid peptides (Abeta) and neurofibrillary tangles (NFTs) formed by hyperphosphorylated tau, a microtubule-associated protein, are the hallmark lesions of Alzheimer's disease (AD) in addition to loss of neurons. While several transgenic (Tg) (…)
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[Source: NCBI PubMed]
PRIMARY OBJECTIVES: To investigate the measurement properties of the Orientation Log (O-Log) and a hybrid scale using Rasch analysis techniques and to explore the relations between the items of the 2 scales and the latent linear construct modeled in the Rasch analysis. (…)
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[Source: NCBI PubMed]
INTRODUCTION: A prespecified analysis of the large, randomized, phase III study in advanced non-small cell lung cancer showed significant improvement in survival for nonsquamous patients treated with pemetrexed/cisplatin versus gemcitabine/cisplatin. Selected grade 3/4 (…)
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[Source: NCBI PubMed]
6 September 2010 - Circadian Technologies Limited (ASX:CIR) announced today that its subsidiary company, Vegenics Limited, has been granted US Patent 7785803 claiming diagnostic kits for the detection of VEGF-D in human samples such as blood. VEGF-D, a major novel target for (…)
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[Source: BioSpace]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/e3fec8/mens_health_thera) has announced the addition of the "Men's Health Therapeutics Market to 2016 - Selective Serotonin Reuptake Inhibitors, Hormone Replacement Therapy and (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/61183d/womens_health_the) has announced the addition of the "Women's Health Therapeutics, Analysis and Market Forecasts to 2016 - High Unmet Need will Drive the Uptake of Novel Drugs in (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/fe4133/urological_disorde) has announced the addition of the "Urological Disorders Therapeutics to 2016 - Increasing Awareness and Aging Population will Drive the Benign Prostatic (…)
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[Source: Business Wire]
Cancer Research UK's Drug Development Office has launched a clinical trial* to test an experimental drug in patients with advanced (Stage IV) pancreatic cancer - one of the most difficult cancers to treat. Around 60 patients with advanced pancreatic cancer will be recruited for (…)
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[Source: Medical News Today]
Actavis has received approval from the U.S. Food & Drug Administration to market Atomoxetine HCl capsules for the treatment of attention deficit/hyperactivity disorder (ADHD). Actavis intends to market Atomoxetine HCl in 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg and 100 mg (…)
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[Source: Medical News Today]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/66a1b1/philippines_pharma) has announced the addition of the "Philippines Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Philippines Pharmaceuticals and (…)
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[Source: Business Wire]
MUMBAI, India-(BUSINESS WIRE)-Sun Pharmaceutical Industries Ltd. (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE:SUNPHARMA, BSE: 524715) announced that USFDA has granted its subsidiary an approval for its Abbreviated New Drug Application (ANDA) to market a generic version of (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/46792f/poland_pharmaceuti) has announced the addition of the "Poland Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Poland Pharmaceuticals and Healthcare Report (…)
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[Source: Business Wire]
Flagstaff, AZ (PRWEB) August 27, 2010 - Flagship Biosciences LLC, a provider of digital pathology services, has formed a Scientific Advisory Board composed of experienced leaders in the pharmaceutical industry. Flagship is a pathologist-owned company committed to improving the (…)
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[Source: BioSpace]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/37adf0/eli_lilly_co_p) has announced the addition of the "Eli Lilly & Co.: PharmaVitae Profile" company profile to their offering. Introduction This analysis examines the historical and (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/d141a8/strategies_for_man) has announced the addition of the "Strategies for Managing Pharmaceutical Workforce and Site Reductions: Analysis of Legal, Productivity, and Quality Control (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/aabcf1/johnson_johnson) has announced the addition of the "Johnson & Johnson: PharmaVitae Profile" company profile to their offering. Introduction This analysis examines the historical and (…)
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[Source: Business Wire]
Sermo, the world's largest online community for physicians, announced a free Sermo Report titled, "FDA Committee Recommends Approval for Ticagrelor." The report covers physician opinions about the introduction of an investigational oral antiplatelet treatment for acute coronary (…)
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[Source: Medical News Today]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/db0b08/type_2_diabetes) has announced the addition of GlobalData 's new report "Type 2 Diabetes - Pipeline Assessment and Market Forecasts to 2017" to their offering. Type 2 Diabetes - (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/883f56/novel_antibodies_a) has announced the addition of the "Novel Antibodies and Therapeutic Proteins - Technology Challenges and Future Prospects" report to their offering. Novel (…)
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[Source: Business Wire]
Delamination, or the generation of glass flakes in vials used to contain parenteral drug products, continues to be a persistent problem in the pharmaceutical industry. To understand all of the factors that might contribute to delamination, a statistical design of experiments (…)
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[Source: NCBI PubMed]
CAMBRIDGE, Mass.-(BUSINESS WIRE)-Idera Pharmaceuticals, Inc. (Nasdaq: IDRA - News), today announced that it has achieved a milestone under its worldwide licensing and collaboration agreement with Merck KGaA, Darmstadt, Germany. The milestone was achieved upon Merck KGaA s (…)
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[Source: BioSpace]
NEW YORK, Aug 27 (Reuters) - A federal appeals court has extended a temporary order blocking 10 companies from selling generic versions of Eli Lilly and Co's (LLY.N) Strattera attention deficit disorder drug.
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[Source: BioSpace]
Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the increased generic erosion of key drugs such as lamotrigine (GlaxoSmithKline's Lamictal, generics) and divalproex (Abbott/Sanofi-Aventis's (…)
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[Source: Medical News Today]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/e03d6e/world_pharmaceutic) has announced the addition of the "World Pharmaceutical Market Analysis - A Digest Guide, 2010-2014" report to their offering. World Pharmaceutical Market (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Genetically Modified Organisms research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not (…)
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[Source: Business Wire]
GENEVA-(BUSINESS WIRE)-Dr. Jürgen Raths has been appointed President and CEO of Iroko Cardio International Sà rl, a newly created business entity focusing on the commercialization of Aggrastat (Tirofiban) world-wide outside the USA. Iroko Cardio International operates out (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Smoking Cessation research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Antibacterial research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise visible (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/669c07/online_healthcare) has announced the addition of eMarketer's new report "Online Healthcare Empowers Consumers" to their offering. Healthcare consumers go online for an increasing (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Tissue Banking research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise (…)
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[Source: Business Wire]
Proteins. |-| Sampathkumar P, Lu F, Zhao X, Li Z, Gilmore J, Bain K, Rutter ME, Gheyi T, Schwinn KD, Bonanno JB, Pieper U, Fajardo JE, Fiser A, Almo SC, Swaminathan S, Chance MR, Baker D, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Sali A, Sauder JM, Burley SK. |-| New York (…)
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[Source: NCBI PubMed]