News: Merck & Co.

09.09.2010 | Business Wire: Research and Markets: Introducing 2010 Report 'Influenza Vaccine Manufacturing: Can New Technologies Open the Production Bottleneck?' | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets(http:/www.researchandmarkets.com/research/77bfe1/influenza_vaccine) has announced the addition of Decision Resources, Inc.'s new report "Influenza Vaccine Manufacturing: Can New Technologies Open the Production Bottleneck?" to (…)

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[Source: Business Wire]

01.01.2010 | NCBI PubMed: Attitudes, Awareness, Compliance and Preferences among Hormonal Contraception Users: A Global, Cross-Sectional, Self-Administered, Online Survey.

Background: Healthcare professionals have a responsibility to help each woman select the most appropriate hormonal contraceptive according to her personal preferences, needs and circumstances. Objective: To assess attitudes, awareness, compliance and preferences of hormonal (…)

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[Source: NCBI PubMed]

01.09.2010 | NCBI PubMed: Small-molecule PARP modulators - Current status and future therapeutic potential.

PARP-1 inhibitors have emerged as a promising therapeutic class of compounds, and numerous PARP inhibitors, including iniparib (BiPar Sciences Inc/sanofi-aventis), olaparib (AstraZeneca plc), veliparib (Abbott Laboratories), PF-1367338 (Pfizer Inc), MK-4827 (Merck & Co Inc) and (…)

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[Source: NCBI PubMed]

26.05.2010 | NCBI PubMed: Risk assessment and physicochemical characterization of a metastable dihydrate API phase for intravenous formulation development.

(1S,5R)-2-{[(4S)-azepan-4-ylamino]carbonyl}-7-oxo-2,6-diazabicyclo[3.2.0] heptane-6-sulfonic acid (Compound 1) is a beta-lactamase inhibitor for intravenous administration. The objective of this preformulation study was to determine the most appropriate form of the API for (…)

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[Source: NCBI PubMed]

07.09.2010 | NCBI PubMed: Ethical considerations in industry-sponsored Multiregional clinical trials.

During the last several decades, the scientific and ethics communities have addressed important ethical issues in medical research, resulting in the elaboration and adoption of concepts, guidelines, and codes.Ethical issues in the conduct of Multiregional Clinical Trials have (…)

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[Source: NCBI PubMed]

27.08.2010 | NCBI PubMed: Estimating chromatographic enantioselectivity (alpha) from gradient enantioselective chromatography data.

Calculation of chromatographic enantioselectivity (alpha) is critically important in enantioselective chromatographic method development studies. The fact that alpha can only be calculated from isocratic elution conditions, whereas gradient elution conditions are predominantly (…)

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[Source: NCBI PubMed]

31.08.2010 | NCBI PubMed: Medicinal Chemistry of siRNA Delivery.

J Med Chem. |-| Stanton MG, Colletti SL. |-| Department of Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, Pennsylvania 19486.

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[Source: NCBI PubMed]

08.09.2010 | BioSpace: Addex Pharmaceuticals (ADXN.SW) Awarded Michael J. Fox Foundation Grant for ADX48621 to Treat Levodopa-Induced Dyskinesia in Parkinson's Disease

Geneva, Switzerland, 8 September 2010 - Allosteric modulation company Addex Pharmaceuticals Ltd (SIX:ADXN) announced today that it has been awarded a $900,000 grant from The Michael J. Fox Foundation (MJFF) to help fund a Phase II study of ADX48621 for the treatment of (…)

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[Source: BioSpace]

08.09.2010 | BioSpace: Karo Bio AB Announces That Merck & Co., Inc. (MRK) Discontinues Development of Mk-6913 for Hot Flashes

Sep 08, 2010 (NORDIC BUSINESS REPORT via COMTEX) -8 September 2010 - Swedish drug developer Karo Bio AB (STO: KARO) has been notified by its US partner Merck & Co Inc (NYSE: MRK | PowerRating) that it decided to discontinue the development of their joint drug candidate MK-6913 (…)

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[Source: BioSpace]

07.09.2010 | Marketwire: Addex Awarded Michael J. Fox Foundation Grant for ADX48621 to treat Levodopa-Induced Dyskinesia in Parkinson's Disease

GENEVA, SWITZERLAND-(Marketwire - September 7, 2010) - Addex Pharmaceuticals / Addex Awarded Michael J. Fox Foundation Grant for ADX48621 to treat Levodopa-Induced Dyskinesia in Parkinson's Disease processed and transmitted by Hugin AS. The issuer is solely responsible for the (…)

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[Source: Marketwire]

07.09.2010 | BioSpace: Galapagos NV (GLPG.BR) Announces Appointment Of Howard Rowe To Board Of Directors, Increases Share Capital Through Warrant Exercises

MECHELEN, BELGIUM-(Marketwire - September 07, 2010) - Galapagos NV (Euronext: GLPG) announced today that its Board of Directors has appointed Mr. Howard Rowe as an Independent Director of the Company. Furthermore, Galapagos announced a capital increase arising from employee (…)

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[Source: BioSpace]

06.09.2010 | Business Wire: Research and Markets: Women's Health Therapeutics, Analysis and Market Forecasts to 2016 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/61183d/womens_health_the) has announced the addition of the "Women's Health Therapeutics, Analysis and Market Forecasts to 2016 - High Unmet Need will Drive the Uptake of Novel Drugs in (…)

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[Source: Business Wire]

06.09.2010 | Business Wire: Research and Markets: Epigenetics Therapeutics to 2017 - High Market Potential for Epigenetics Drugs in Acute Myeloid Leukemia, Multiple Myeloma and Cutaneous T-Cell Lymphoma | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/f7e7a7/epigenetics_therap) has announced the addition of the "Epigenetics Therapeutics to 2017 - High Market Potential for Epigenetics Drugs in Acute Myeloid Leukemia, Multiple Myeloma and (…)

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[Source: Business Wire]

03.09.2010 | Business Wire: Research and Markets: Thailand Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/60383e/thailand_pharmaceu) has announced the addition of the "Thailand Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Thailand Pharmaceuticals and Healthcare (…)

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[Source: Business Wire]

02.09.2010 | Medical News Today: Trial To Test Experimental Drug For Advanced Pancreatic Cancer

Cancer Research UK's Drug Development Office has launched a clinical trial* to test an experimental drug in patients with advanced (Stage IV) pancreatic cancer - one of the most difficult cancers to treat. Around 60 patients with advanced pancreatic cancer will be recruited for (…)

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[Source: Medical News Today]

02.09.2010 | Business Wire: MSD Receives European Approval of its Atypical Antipsychotic Medication SYCREST (asenapine) for the Treatment of Manic Episodes in Bipolar I Disorder | Business Wire

WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-MSD (MSD is a tradename of Merck & Co., Inc., with headquarters in Whitehouse Station, N.J., U.S.A). announced today that the European Commission has approved the Marketing Authorization Application (MAA) for SYCREST (asenapine) (…)

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[Source: Business Wire]

02.09.2010 | BioSpace: EU Marketing Approval for IV Brinavess, Treatment for Atrial Fibrillation

Merck & Co and partner Cardiome Pharma Corp have been granted marketing approval by European regulators for the intravenous formulation of their anti-arrhythmic Brinavess. The European Union, Iceland and Norway have given the green light to Brinavess (vernakalant) for the rapid (…)

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[Source: BioSpace]

02.09.2010 | BioSpace: Merck & Co., Inc. (MRK) Postpones Dutch Closures, Options Open

AMSTERDAM, Sept 2 (Reuters) - U.S. drugmaker Merck & Co (MRK.N) has postponed the closure of some of its Dutch operations while it negotiates with executives and workers on potential alternatives, including a sale of the R&D site.

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[Source: BioSpace]

02.09.2010 | BioSpace: Addex Pharmaceuticals (ADXN.SW) Drug-Candidate Effective in Alzheimer's Disease Model

GENEVA, SWITZERLAND-(Marketwire - September 02, 2010) - Addex Pharmaceuticals / Addex drug-candidate effective in Alzheimer's disease model processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. Allosteric modulation (…)

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[Source: BioSpace]

02.09.2010 | BioSpace: AIDS Cure Quest to Kill 'Sleeping' Viruses Enlists Merck & Co., Inc. (MRK) Cancer Medicine, University of North Carolina Study

Bloomberg - The 30-year-long search for a cure for AIDS, the world s deadliest viral infection, may get a renewed boost from an unlikely source: a little-used Merck & Co. cancer drug.

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[Source: BioSpace]

02.09.2010 | BioSpace: Cardiome Pharma Corp. (COM.TO) Gets Nod For Marketing Heart Drug In EU; Receives $30 Million From Merck Sharp & Dohme (MRK)

VANCOUVER, Sept. 2 /PRNewswire-FirstCall/ - Cardiome Pharma Corp. (NASDAQ:CRME - News) today announced that it has earned a US$30 million milestone payment from its collaboration with Merck (known as MSD outside the United States and Canada), through an affiliate. The milestone (…)

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[Source: BioSpace]

02.09.2010 | BioSpace: Merck & Co., Inc. (MRK) Receives European Approval of its Atypical Antipsychotic Medication SYCREST(R) (asenapine) for the Treatment of Manic Episodes in Bipolar I Disorder

WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-MSD (MSD is a tradename of Merck & Co., Inc., with headquarters in Whitehouse Station, N.J., U.S.A). announced today that the European Commission has approved the Marketing Authorization Application (MAA) for SYCREST (asenapine) (…)

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[Source: BioSpace]

01.09.2010 | Business Wire: Research and Markets: Argentina Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/2745c9/argentina_pharmace) has announced the addition of the "Argentina Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Argentina Pharmaceuticals and Healthcare (…)

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[Source: Business Wire]

01.09.2010 | Business Wire: BRINAVESS ¢ (vernakalant) for Infusion Approved in the European Union for Rapid Conversion of Recent Onset Atrial Fibrillation | Business Wire

WHITEHOUSE STATION, N.J. & VANCOUVER, British Columbia-(BUSINESS WIRE)-Merck (known as MSD outside the United States and Canada) (NYSE:MRK) and Cardiome Pharma Corp. (NASDAQ: CRME/ TSX: COM) today announced that the intravenous (IV) formulation of BRINAVESS ¢ (vernakalant) (…)

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[Source: Business Wire]

01.09.2010 | Business Wire: BRINAVESS ¢ (vernakalant) for Infusion Approved in the European Union for Rapid Conversion of Recent Onset Atrial Fibrillation | Business Wire

WHITEHOUSE STATION, N.J. U.S.A. & VANCOUVER, British Columbia-(BUSINESS WIRE)-MSD (known in the US and Canada as Merck) (NYSE:MRK) and Cardiome Pharma Corp. (NASDAQ: CRME/ TSX: COM) today announced that the intravenous (IV) formulation of BRINAVESS ¢ (vernakalant) has been (…)

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[Source: Business Wire]

01.09.2010 | BioSpace: Theratechnologies Inc. (TH.TO) is Pleased to Announce the Appointment of a New President and CEO

MONTREAL, CANADA-(Marketwire - September 01, 2010) - Theratechnologies (TSX: TH) announced today the appointment of Mr. John-Michel T. Huss as President and Chief Executive Officer of the Company. Mr. Huss will assume his responsibilities in the coming months. Until recently, (…)

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[Source: BioSpace]

31.08.2010 | Business Wire: Research and Markets: Philippines Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/66a1b1/philippines_pharma) has announced the addition of the "Philippines Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Philippines Pharmaceuticals and (…)

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[Source: Business Wire]

31.08.2010 | Business Wire: Research and Markets: Nigeria Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/23871e/nigeria_pharmaceut) has announced the addition of the "Nigeria Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Nigeria Pharmaceuticals and Healthcare Report (…)

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[Source: Business Wire]

31.08.2010 | BioSpace: BioCision, LLC Signs Agreement with SERVA Electrophoresis GmbH for Distribution of CoolTech Products in Europe

MILL VALLEY, Calif. - March 26, 2010 - BioCision LLC today announced that it has signed a European distribution agreement with SERVA Electrophoresis, a global supplier of reagents for scientific research. SERVA Electrophoresis will sell BioCision s entire portfolio of (…)

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[Source: BioSpace]

31.08.2010 | BioSpace: BioCision, LLC Lands New Distribution Partner with Biophoretics Deal

MILL VALLEY, Calif. February 11, 2010 - BioCision LLC, the CoolRack ¢ company, announced today that it has entered into a distribution agreement with Biophoretics, a developer and distributor of advanced tools for scientific research. Biophoretics will sell BioCision s entire (…)

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[Source: BioSpace]

31.08.2010 | BioSpace: BioCision, LLC Signs Distribution Deal with Capital Biosciences, Inc.

MILL VALLEY, Calif. - BioCision LLC, the CoolRack ¢ company, announced today that is has reached an agreement with Capital Biosciences Inc. for the distribution of BioCision's products, which standardize the handling and processing of temperature-sensitive samples. œCapital (…)

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[Source: BioSpace]

30.08.2010 | Business Wire: Research and Markets: This Essential Analysis Examines the Historical and Forecast Performance for Eli Lilly In the Prescription Pharma Sector | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/37adf0/eli_lilly_co_p) has announced the addition of the "Eli Lilly & Co.: PharmaVitae Profile" company profile to their offering. Introduction This analysis examines the historical and (…)

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[Source: Business Wire]

30.08.2010 | Business Wire: Research and Markets: Stakeholder Opinions: Sexually Transmitted Diseases - An Underestimated Threat Lacking Interventions to Prevent Transmission | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/f02991/stakeholder_opinio) has announced the addition of the "Stakeholder Opinions: Sexually Transmitted Diseases - An Underestimated Threat Lacking Interventions to Prevent Transmission" (…)

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[Source: Business Wire]

30.08.2010 | BioSpace: BioCision, LLC and Biohit Partner to Co-Promote Complementary Products

MILL VALLEY, Calif., March 31 /PRNewswire/ - BioCision LLC today announced that it has agreed to a co-promotion program with Biohit Inc. (www.us.biohit.com). Biohit's ErgoTube microcentrifuge tubes will now be branded and sold by both Biohit Inc. and BioCision. In addition, (…)

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[Source: BioSpace]

30.08.2010 | BioSpace: Portola Pharmaceuticals, Inc. Announces That Phase 2 INNOVATE-PCI Trial With Elinogrel Achieved Objectives; Novartis AG to Start Final-Stage Test of Blood Thinner

STOCKHOLM, SWEDEN-(Marketwire - August 30, 2010) - Portola Pharmaceuticals, Inc. today announced results from the Phase 2 INNOVATE-PCI study of its investigational antiplatelet drug, elinogrel, the only competitive, reversible direct-acting P2Y12 ADP receptor antagonist. (…)

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[Source: BioSpace]

27.08.2010 | Business Wire: Research and Markets: Type 2 Diabetes - Pipeline Assessment and Market Forecasts to 2017 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/db0b08/type_2_diabetes) has announced the addition of GlobalData 's new report "Type 2 Diabetes - Pipeline Assessment and Market Forecasts to 2017" to their offering. Type 2 Diabetes - (…)

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[Source: Business Wire]

26.08.2010 | Business Wire: Research and Markets: This Essential World Pharmaceutical Market Analysis Digest Guide with Forecasts Predicts the Market Will Stabilize the Years Up To 2014 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/e03d6e/world_pharmaceutic) has announced the addition of the "World Pharmaceutical Market Analysis - A Digest Guide, 2010-2014" report to their offering. World Pharmaceutical Market (…)

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[Source: Business Wire]

26.08.2010 | Business Wire: Research and Markets: Women's Infertility - Pipeline Assessment and Market Forecasts to 2017 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/364cde/women's_infertilit) has announced the addition of GlobalData 's new report "Women's Infertility - Pipeline Assessment and Market Forecasts to 2017" to their offering. Women's (…)

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[Source: Business Wire]

26.08.2010 | Business Wire: Research and Markets: Examine the US Pharmaceutical Market with This Essential Analysis and Forecast to 2014 As the Market Generated Total Revenues of $276,681.9 Million In 2009 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/3373b4/us_pharmaceutical) has announced the addition of the "US Pharmaceutical Market Analysis, 2010-2014" report to their offering. Having displayed decelerating growth rates in the years (…)

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[Source: Business Wire]

24.08.2010 | NCBI PubMed: Asymmetric Hydrogenation of Protected Allylic Amines.

A general method for the enantioselective hydrogenation of protected allylic amine derivatives is described. This procedure relies on the generation of a cationic ruthenium complex with the axially chiral ligand (-)-TMBTP. The utility is highlighted by the highly (…)

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[Source: NCBI PubMed]

25.08.2010 | Business Wire: Maven Semantic: Biomarker Research Database | Business Wire

DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Biomarker research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise visible - (…)

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[Source: Business Wire]

25.08.2010 | BioSpace: Addex Pharmaceuticals (ADXN.SW) Partner Completes ADX71149 Phase I Program

GENEVA, SWITZERLAND-(Marketwire - August 25, 2010) - Addex Pharmaceuticals / Addex Partner Completes ADX71149 Phase I Program processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. Geneva, Switzerland, 25 August 2010 - (…)

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[Source: BioSpace]