News: Roche

06.09.2010 | Business Wire: Research and Markets: Women's Health Therapeutics, Analysis and Market Forecasts to 2016 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/61183d/womens_health_the) has announced the addition of the "Women's Health Therapeutics, Analysis and Market Forecasts to 2016 - High Unmet Need will Drive the Uptake of Novel Drugs in (…)

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[Source: Business Wire]

06.09.2010 | Business Wire: Research and Markets: Cancer Drug Resistance Report: the Single Most Important Cause of Cancer Treatment Failure | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/41867b/cancer_drug_resist) has announced the addition of the "Cancer Drug Resistance" report to their offering. Drug resistance is the single most important cause of cancer treatment (…)

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[Source: Business Wire]

03.09.2010 | Business Wire: Exelixis Reports Inducement Grants Under Nasdaq Listing Rule 5635(C)(4) | Business Wire

SOUTH SAN FRANCISCO, Calif.-(BUSINESS WIRE)-Exelixis, Inc. (Nasdaq:EXEL) announced that today it granted restricted stock units representing an aggregate of 25,200 shares of Exelixis common stock to nine new employees. The restricted stock unit awards vest as to 1/4th of the (…)

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[Source: Business Wire]

03.09.2010 | Business Wire: ImmunoCellular Therapeutics Issues Letter to Shareholders | Business Wire

LOS ANGELES-(BUSINESS WIRE)-ImmunoCellular Therapeutics (OTCBB: IMUC) issued the following Letter to Shareholders today: Dear Shareholders, As the summer comes to a close, I wanted to update you on the Company s accomplishments this year, which set the stage for an exciting (…)

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[Source: Business Wire]

03.09.2010 | BioSpace: Roche (RHHBY) to Cut Costs, Review Business After Drug Setbacks; No Details on Size of Cost Reductions or the Number of Staff, Units Affected, Detailed Steps Will be Announced Late 2010

ZURICH/BASEL, Sept 3 (Reuters) - Swiss drugmaker Roche Holding AG (ROG.VX) will review its business and cut costs to cope with recent setbacks on key drugs and rising pressures on prices from healthcare reforms, it said on Friday.

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[Source: BioSpace]

02.09.2010 | Medical News Today: Roche Provides Update On FDA Application For T-DM1

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that the U.S. Food and Drug Administration (FDA) issued a Refuse to File letter for accelerated approval for the company's trastuzumab-DM1 (T-DM1) Biologics License Application (BLA). As planned Roche will continue with its ongoing (…)

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[Source: Medical News Today]

02.09.2010 | Medical News Today: Siemens Executive Appointed President Of IVD Industry Connectivity Consortium

Siemens Healthcare Diagnostics announces Eric Olson's appointment as President of the IVD Industry Connectivity Consortium (IICC). Founded by the top worldwide in vitro diagnostics (IVD) manufacturers, IICC's mission is to create and ensure adoption of a unified connectivity (…)

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[Source: Medical News Today]

02.09.2010 | Business Wire: ImmunoGen, Inc. Announces Webcast of Presentations at Multiple Investor Conferences in September | Business Wire

WALTHAM, Mass.-(BUSINESS WIRE)-ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops antibody-based targeted anticancer products, today announced that Company management will present at multiple investor conferences this month. The live webcast of each (…)

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[Source: Business Wire]

02.09.2010 | Business Wire: RegeneRx Appoints R. Don Elsey to Board of Directors | Business Wire

ROCKVILLE, Md.-(BUSINESS WIRE)-RegeneRx Biopharmaceuticals, Inc. (NYSE Amex:RGN) ( œthe Company  or œRegeneRx ) today announced that R. Don Elsey has been appointed to the Company s board of directors, effective September 1. Mr. Elsey will serve on the compensation and (…)

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[Source: Business Wire]

02.09.2010 | BioSpace: LGC Genomics Acquires the New Illumina HiSeq 2000

02 September 2010 - The new Illumina HiSeq 2000 is added to LGC Genomics next generation sequencing portfolio LGC Genomics, the genomics division of LGC, announces the acquisition of the latest next generation sequencing technology Illumina HiSeq 2000 to its sequencing (…)

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[Source: BioSpace]

02.09.2010 | BioSpace: Addex Pharmaceuticals (ADXN.SW) Drug-Candidate Effective in Alzheimer's Disease Model

GENEVA, SWITZERLAND-(Marketwire - September 02, 2010) - Addex Pharmaceuticals / Addex drug-candidate effective in Alzheimer's disease model processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. Allosteric modulation (…)

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[Source: BioSpace]

01.09.2010 | Business Wire: Research and Markets: Argentina Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/2745c9/argentina_pharmace) has announced the addition of the "Argentina Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Argentina Pharmaceuticals and Healthcare (…)

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[Source: Business Wire]

01.09.2010 | Business Wire: HTG Announces Appointments of John Wineman as Vice President New Business Development - Western Region and Thomas Vasicek, Ph.D. as Vice President Clinical Programs and Product Innovation | Business Wire

TUCSON, Ariz.-(BUSINESS WIRE)-HTG, Inc., provider of the quantitative Nuclease Protection Assay (qNPA ¢), today announced the appointments of John Wineman as Vice President New Business Development, Western Region and Thomas Vasicek, Ph.D., as Vice President Clinical (…)

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[Source: Business Wire]

01.09.2010 | BioSpace: Theratechnologies Inc. (TH.TO) is Pleased to Announce the Appointment of a New President and CEO

MONTREAL, CANADA-(Marketwire - September 01, 2010) - Theratechnologies (TSX: TH) announced today the appointment of Mr. John-Michel T. Huss as President and Chief Executive Officer of the Company. Mr. Huss will assume his responsibilities in the coming months. Until recently, (…)

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[Source: BioSpace]

01.09.2010 | BioSpace: ThromboGenics Ltd. (THR.BR)'s Microplasmin Meets Primary Endpoint in Second Phase III Trial in VMA, Confirms Positive Findings of First Trial

LEUVEN, Belgium, September 1, 2010 /PRNewswire-FirstCall/ - - Data Presented at ASRS Confirm Previous Phase III Findings and Microplasmin's Potential to Transform the Treatment of Retinal Disorders ThromboGenics NV (Euronext Brussels: THR), a biopharmaceutical company focused (…)

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[Source: BioSpace]

31.08.2010 | Medical News Today: Genentech Receives Refuse To File Letter From FDA For T-DM1

ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops antibody-based targeted anticancer products, announced that Genentech, a member of the Roche Group, announced its receipt of a Refuse to File (RTF) letter from the US Food and Drug Administration (FDA) for (…)

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[Source: Medical News Today]

31.08.2010 | Medical News Today: Improved Tool For Cycling Fitness Developed By UNH Researchers

For competitive bicyclists with goals - whether competing in the Tour de France or aiming for the podium at a local race - faster cycling comes from training regimens based on various zones of exercise intensity. New research from exercise scientists at the University of New (…)

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[Source: Medical News Today]

31.08.2010 | Business Wire: Research and Markets: This Biotechnology in China Industry Profile Is an Essential Resource for Top-Level Data and Analysis | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/6feb42/biotechnology_in_c) has announced the addition of the "Biotechnology in China" report to their offering. The Biotechnology in China industry profile is an essential resource for (…)

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[Source: Business Wire]

31.08.2010 | Business Wire: Ipsen s Half-year 2010 Results | Business Wire

PARIS-(BUSINESS WIRE)-Regulatory News: Above and beyond the transaction with ˜Inspiration and its diversified international presence, the Group continues to secure its future by actively developing its rich R&D pipeline. The Board of Directors of Ipsen (Paris:IPN) (Euronext: (…)

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[Source: Business Wire]

31.08.2010 | BioSpace: Will Roche (RHHBY) Job Cuts Include China Positions?

August 31, 2010 - Roche Holding AG is planning to make œmassive  job cuts soon, according to newspaper reports, involving œmore than several hundreds  of employees around the world including positions in sales, R&D, production and administration. The reduction in (…)

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[Source: BioSpace]

30.08.2010 | ScienceDaily: Improved Tool Developed for Cycling Fitness

ScienceDaily (Aug. 30, 2010) For competitive bicyclists with goals whether competing in the Tour de France or aiming for the podium at a local race faster cycling comes from training regimens based on various zones of exercise intensity. New research from exercise scientists at (…)

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[Source: ScienceDaily]

30.08.2010 | Business Wire: Maven Semantic: Database of Dermatology Research | Business Wire

DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Dermatology research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise visible - (…)

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[Source: Business Wire]

30.08.2010 | BioSpace: BioServe Introduces the BioServe Network

Beltsville, MD, August 30, 2010 - BioServe today launched The BioServe Network (BSN), a network of leading academic, medical, and industry biosample repositories that creates the largest resource of high-quality biosamples for the life science industry. The charter members of (…)

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[Source: BioSpace]

27.08.2010 | Medical News Today: Roche Breast Cancer Drug Trastuzumab-DM1 Review Turned Down By FDA

The Food and Drug Administration (FDA) has issued a Refuse to File letter for accelerated approval of Roche's trastuzumab-DM1 (T-DM1) Biologics License Application, which was submitted in July 2010. Roche had requested accelerated approval for T-DM1 based on the results of a (…)

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[Source: Medical News Today]

27.08.2010 | Medical News Today: Common Blood Cell Variations Not An Independent Predictor Of Adverse Outcomes For European Kidney Disease Patients

Fluctuations in blood composition that often arise from commonly used therapies among kidney disease patients are not an independent predictor of adverse outcomes for European hemodialysis patients, according to a study appearing in an upcoming issue of the Journal of the (…)

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[Source: Medical News Today]

27.08.2010 | Medical News Today: U.S. Hospitals Making Only Modest Gains In Adoption Of Electronic Health Records

Transforming the U.S. health care system from paper-based to electronic-based may improve health care quality and reduce costs, but a new study by researchers from the Harvard School of Public Health (HSPH) suggests that goal is far off. The adoption of basic or comprehensive (…)

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[Source: Medical News Today]

27.08.2010 | Business Wire: Genentech Provides Update on FDA Application for T-DM1 | Business Wire

SOUTH SAN FRANCISCO, Calif.-(BUSINESS WIRE)-Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced the U.S. Food and Drug Administration (FDA) issued a Refuse to File letter for accelerated approval for the company s trastuzumab-DM1 (T-DM1) (…)

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[Source: Business Wire]

27.08.2010 | Business Wire: Research and Markets: Epigenetics: Tools, Diagnostics, Drugs and World Market | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/910f92/epigenetics_tools) has announced the addition of the "Epigenetics: Tools, Diagnostics, Drugs and World Market" report to their offering. Epigenetics: Tools, Diagnostics, Drugs and (…)

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[Source: Business Wire]

27.08.2010 | Business Wire: Research and Markets: Type 2 Diabetes - Pipeline Assessment and Market Forecasts to 2017 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/db0b08/type_2_diabetes) has announced the addition of GlobalData 's new report "Type 2 Diabetes - Pipeline Assessment and Market Forecasts to 2017" to their offering. Type 2 Diabetes - (…)

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[Source: Business Wire]

25.08.2010 | NCBI PubMed: Piragliatin (RO4389620), a Novel Glucokinase Activator, Lowers Plasma Glucose Both in the Postabsorptive State and after a Glucose Challenge in Patients with Type 2 Diabetes Mellitus: A Mechanistic Study.

Context: Glucokinase plays a key role in glucose homeostasis. Glucokinase activators can lower glucose levels in both animal and human type 2 diabetes, but their mechanism of action has never been explored in humans. Objective: The objective of the study was to investigate the (…)

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[Source: NCBI PubMed]

01.09.2010 | NCBI PubMed: Cytogenetic assessment of heterogeneous radiation doses in cancer patients treated with fractionated radiotherapy.

The purpose of this study was to evaluate the in vivo dose-response relation of chromosome aberration formation and distribution in a context of localised and fractionated radiotherapy. Cytogenetic analysis was applied to eight patients, all treated for the same tumour (…)

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[Source: NCBI PubMed]

26.08.2010 | NCBI PubMed: No clinically relevant drug-drug interactions when dalcetrapib is co-administered with atorvastatin.

Objectives: Dalcetrapib, which targets cholesteryl ester transfer protein, is in clinical development for prevention of cardiovascular events and is likely to be used concomitantly with statins. Two studies investigated co-administration of dalcetrapib with atorvastatin and any (…)

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[Source: NCBI PubMed]

25.08.2010 | NCBI PubMed: Course of dermal ulcers and musculoskeletal involvement in systemic sclerosis patients in the scleroderma lung study.

OBJECTIVE.: To evaluate changes in vascular and musculoskeletal involvement in subjects in the Scleroderma Lung Study (SLS), a multicenter, double-blind, randomized, controlled trial comparing placebo treatment to oral cyclophosphamide for 1 year in systemic sclerosis (SSc) (…)

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[Source: NCBI PubMed]

25.08.2010 | NCBI PubMed: Digital expression profiling of novel diatom transcripts provides insight into their biological functions.

ABSTRACT: BACKGROUND: Diatoms represent the predominant group of eukaryotic phytoplankton in the oceans and are responsible for around 20% of global photosynthesis. Two whole genome sequences are now available. Notwithstanding, our knowledge of diatom biology remains limited (…)

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[Source: NCBI PubMed]

27.08.2010 | BioSpace: Genentech (RHHBY), ImmunoGen, Inc. (IMGN) Receives Refuse to File Letter from FDA for Drug T-DM1, Immunogen Stock Drops 36.35% at 1:49 PM EDT

WALTHAM, Mass.-(BUSINESS WIRE)-ImmunoGen, Inc. (Nasdaq: IMGN - News), a biotechnology company that develops antibody-based targeted anticancer products, today announced that Genentech, a member of the Roche Group, today announced its receipt of a Refuse to File (RTF) letter (…)

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[Source: BioSpace]

27.08.2010 | BioSpace: ThromboGenics NV Announces 2010 First Half Results

Leuven, Belgium 26 August, 2010 ThromboGenics NV (Euronext Brussels: THR), a biopharmaceutical company focused on the discovery and development of innovative treatments for eye disease, cardiovascular disease and cancer, is today issuing a business update in conjunction with (…)

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[Source: BioSpace]

26.08.2010 | ScienceDaily: Advanced Melanoma: New Targeted Therapy Successful in More Than 80 Percent of Patients

ScienceDaily (Aug. 26, 2010) Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial. Results of the trial of PLX4032, an inhibitor of a protein (…)

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[Source: ScienceDaily]

26.08.2010 | ScienceDaily: US Hospitals Making Only Modest Gains in Adoption of Electronic Health Records

ScienceDaily (Aug. 26, 2010) Transforming the U.S. health care system from paper-based to electronic-based may improve health care quality and reduce costs, but a new study by researchers from the Harvard School of Public Health (HSPH) suggests that goal is far off. The (…)

[Read article]

[Source: ScienceDaily]

26.08.2010 | Medical News Today: New Targeted Therapy For Advanced Melanoma Associated With 80% Response Rate

A multicenter study has concluded that treatment with a new targeted therapy called PLX4032 (also called RG7204) resulted in significant tumor shrinkage in 80 percent of patients with advanced melanoma. Investigators at Memorial Sloan-Kettering Cancer Center and colleagues at (…)

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[Source: Medical News Today]

26.08.2010 | Medical News Today: Ambry Genetics Announces The Addition Of Illumina HiSeq 2000 And First 510(K) Approved BeadXpress To Its Sequencing And Genotyping Capabilities

Ambry Genetics, a global leader in genomic services, announced that it has acquired the Illumina HiSeq 2000 Next Generation Sequencing System as well as received the first 510(K) approved Illumina BeadXpress Genotyping System. Ambry Genetics has been an early adapter of (…)

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[Source: Medical News Today]

26.08.2010 | Medical News Today: Experimental Drug That Targets BRAF Cancer Gene Shows Promise Against Metastatic Melanoma

A phase 1 clinical trial using a new formulation of an experimental drug that targets the BRAF cancer gene, has shown early promise in treating melanoma in patients with a mutated form of the gene and whose skin cancer has progressed to the metastatic stage. A paper on the (…)

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[Source: Medical News Today]

26.08.2010 | Medical News Today: USA Today Publishes Opposing Opinions On Avastin For Breast Cancer Treatment

USA Today recently published an editorial and an opinion piece regarding the recent controversy surrounding the cancer drug Avastin. An FDA advisory panel in July voted 12-1 to recommend that the agency revoke Avastin's approval to treat advanced breast cancer after two (…)

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[Source: Medical News Today]