Netilmicin is a semi-synthetic aminoglycoside antibiotic used against a broad spectrum of Gram-negative bacteria. A reversed-phase high-performance liquid chromatographic method has been developed to determine the composition of netilmicin sulfate and to estimate its related (…)
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[Source: NCBI PubMed]
Breaking News - Some 160 jobs are to go at the Schering Plough pharmaceutical plant in west Cork, it emerged this afternoon.
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[Source: BioSpace]
OBJECTIVE: To determine the antithrombotic effects of SCH 602539, an analog of the selective protease-activated receptor (PAR)-1 antagonist vorapaxar (formerly SCH 530348) currently in advanced clinical development, and the P2 years12 ADP receptor antagonist cangrelor, alone (…)
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[Source: NCBI PubMed]
PARIS-(Marketwire - September 7, 2010) - Cegedim Strategic Data, leading provider of integrated healthcare research, announces the results of its international Rep Quality Survey. As emerging markets remain a focus area for growth for the pharmaceutical industry, CSD conducted (…)
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[Source: Marketwire]
NEW YORK-(BUSINESS WIRE)-Gleacher & Company Securities, Inc., a broker-dealer subsidiary of Gleacher & Company, Inc. (Nasdaq: GLCH), today announced another addition to its Healthcare Research team with the hiring of Ying Huang. I continue to believe that expanding our equity (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-MSD (MSD is a tradename of Merck & Co., Inc., with headquarters in Whitehouse Station, N.J., U.S.A). announced today that the European Commission has approved the Marketing Authorization Application (MAA) for SYCREST (asenapine) (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J. & VANCOUVER, British Columbia-(BUSINESS WIRE)-Merck (known as MSD outside the United States and Canada) (NYSE:MRK) and Cardiome Pharma Corp. (NASDAQ: CRME/ TSX: COM) today announced that the intravenous (IV) formulation of BRINAVESS ¢ (vernakalant) (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J. U.S.A. & VANCOUVER, British Columbia-(BUSINESS WIRE)-MSD (known in the US and Canada as Merck) (NYSE:MRK) and Cardiome Pharma Corp. (NASDAQ: CRME/ TSX: COM) today announced that the intravenous (IV) formulation of BRINAVESS ¢ (vernakalant) has been (…)
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[Source: Business Wire]
27.08.2010 - Regenicin, Inc., a clinical-stage biotechnology company, announced that Dr. Joseph Rubinfeld, one of the four original founders of Amgen, Inc., has agreed to join the company's board of directors. Dr. Rubinfeld will be instrumental to assisting the compan's (…)
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[Source: Bionity.com]
DURHAM, NC, and LIEGE, BELGIUM - August 26, 2010 - OncoMethylome Sciences (Euronext Brussels: ONCOB, Euronext Amsterdam: ONCOA), a leading molecular diagnostics company, announced today its 2010 half-year results and its new strategy. Highlights: Strategic/Commercial: Cervical (…)
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[Source: BioSpace]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/81e154/raising_disease_st) has announced the addition of the "Raising Disease State Awareness: Best Practices in Internal Brand Messaging for New Products" report to their offering. (…)
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[Source: Business Wire]
The clastogenic potential of a recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) therapeutic protein formulation was assessed in human peripheral blood lymphocyte (HPBL) cultures. Final formulation, rather than pure protein, was evaluated to simulate (…)
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[Source: NCBI PubMed]
Equine influenza is a contagious disease caused by equine influenza virus which belongs to the orthomyxovirus family. Outbreaks of equine influenza cause severe economic loses to the horse industry and consequently horses in competition are required to be regularly vaccinated (…)
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[Source: NCBI PubMed]
PURPOSE: Benign prostatic hyperplasia is a common urinary tract disorder that affects aging men. The molecular mechanisms underlying benign prostatic hyperplasia are obscure and the development of animal models to test novel treatment strategies is challenging. We report that (…)
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[Source: NCBI PubMed]
August 24, 2010 Caris Life Sciences(TM), Inc., a leading biosciences company focused on enabling precise and personalized healthcare through the highest-quality anatomic pathology, molecular profiling, and blood-based diagnostic technologies, announced today that Winston K.C. (…)
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[Source: BioSpace]
The gamma-glutamyl carboxylase utilizes four substrates to catalyze carboxylation of certain glutamic acid residues in vitamin K-dependent proteins. How the enzyme brings the substrates together to promote catalysis is an important question in understanding the structure and (…)
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[Source: NCBI PubMed]
Francisella asiatica is a recently described, Gram negative, facultative intracellular fish pathogen, known to be the causative agent of francisellosis in warmwater fish. Francisellosis outbreaks have increased in frequency amongst aquaculture commercial operations, and have (…)
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[Source: NCBI PubMed]
The American Pharmacists Association (APhA) and the Academy of Managed Care Pharmacy (AMCP) announced the launch of AMCP/APhA MTM ConnectionsTM - an online resource to advance the implementation of medication therapy management and other clinical services by pharmacists and (…)
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[Source: Medical News Today]
EMERYVILLE, Calif.-(BUSINESS WIRE)-The American Heart Association (AHA) has honored KineMed s abstract entitled Ezetimibe Treatment Stimulates Transport of Plasma Cholesterol into Fecal Neutral Sterols in Hyperlipidemic Humans with a position in the Best of AHA Specialty (…)
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[Source: Business Wire]
EMERYVILLE, Calif.-(BUSINESS WIRE)-The American Heart Association (AHA) has honored KineMed s abstract entitled Ezetimibe Treatment Stimulates Transport of Plasma Cholesterol into Fecal Neutral Sterols in Hyperlipidemic Humans with a position in the Best of AHA Specialty (…)
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[Source: BioSpace]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Allergy research database. The system uses the context in which a given person appears, using artificial intelligence techniques to find out information not otherwise visible - for (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Merck & Co., Inc. today announced that, as of the close of business on August 13, 2010, the outstanding shares of the company s 6.00% Mandatory Convertible Preferred Stock (NYSE: MRK-PB) will mandatorily convert by their terms into a (…)
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[Source: Business Wire]
A set of high-resolution three-dimensional solution structures of the Src homology region-2 (SH2) domain of the growth factor receptor-bound protein-2 was determined using heteronuclear NMR spectroscopy. The NMR data used in this study were collected on a stable monomeric (…)
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[Source: NCBI PubMed]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Psoriasis research database. , based on where they work, their job title, how many times they have published, where they have published, etc. The relevance can be fine tuned by the (…)
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[Source: Business Wire]
DUBLIN-(BUSINESS WIRE)-Maven Semantic (http:/www.mavensemantic.com) announces updates to their Psoriasis research database. , based on where they work, their job title, how many times they have published, where they have published, etc. The relevance can be fine tuned by the (…)
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[Source: Business Wire]
Am J Psychiatry. |-| Nelson JC. |-| The author has received lecture honoraria from Eli Lilly Global, Otsuka Asia, and Schering Plough/Merck (Asia); participated in industry-sponsored CME programs for AstraZeneca, Bristol-Myers Squibb, Forest, and Otsuka; served as a consultant (…)
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[Source: NCBI PubMed]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/045efe/the_pharmaceutical) has announced the addition of the "The Pharmaceutical Market: Brazil" report to their offering. These highly regarded world pharmaceutical market reports have (…)
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[Source: Business Wire]
WALTHAM, Mass.-(BUSINESS WIRE)-Phase Forward Incorporated (NASDAQ: PFWD), a leading provider of data management solutions for clinical trials and drug safety, announced that the United States Department of Justice has closed its investigation of the proposed acquisition of (…)
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[Source: Business Wire]
SOUTH SAN FRANCISCO, Calif., Aug. 5, 2010 (GLOBE NEWSWIRE) - Hana Biosciences (OTCBB:HNAB), a biopharmaceutical company focused on strengthening the foundation of cancer care, today announced the appointment of Robert (Bob) Spiegel, M.D., FACP, to the Company's Board of (…)
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[Source: BioSpace]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Merck today reported that two pivotal Phase III registration studies for boceprevir, its investigational oral hepatitis C protease inhibitor, have been completed and met the primary endpoints: in both studies in patients with chronic (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Merck today reported that two pivotal Phase III registration studies for boceprevir, its investigational oral hepatitis C protease inhibitor, have been completed and met the primary endpoints: in both studies in patients with chronic (…)
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[Source: BioSpace]
DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/c22923/medical_laboratori) has announced the addition of the "Medical Laboratories Industry in Argentina" report to their offering. The following report shows a sectoral diagnosis which (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Merck & Co., Inc. (NYSE: MRK) today announced financial results for the second quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the second quarter of $0.86, which (…)
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[Source: Business Wire]
BACKGROUND; Psoriasis vulgaris is a chronic, relapsing, immune-mediated, potentially devastating disease, influenced by genetic and environmental factors, that can cause substantial morbidity and psychological stress and have a profound negative impact on patient quality of (…)
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[Source: NCBI PubMed]
MIAMI, FL-(Marketwire - July 29, 2010) - Unity Management Group Inc. (PINKSHEETS: UYMG), a Health Resource Company specializing in Physician and Hospital Practice Management, Medical Discount Plans, Business Services, Billing Software and Technologies. Unity Management Group (…)
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[Source: Marketwire]
Purpose: To conduct a pilot study of pegylated interferon alpha 2b (PEGIFNalpha2b) for treatment of ocular surface squamous neoplasia (OSSN). Methods: Three patients with histologically proven OSSN were studied prospectively. Patients were given subconjunctival/perilesional (…)
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[Source: NCBI PubMed]
The clinical possibilities of interferon (IFN) became apparent with early studies demonstrating that it was capable of inhibiting tumor cells in culture and in vivo using animal models. IFN gained the distinction of being the first recombinant cytokine to be licensed in the USA (…)
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[Source: NCBI PubMed]
MADISON, Wis. & LIEGE, Belgium-(BUSINESS WIRE)-Exact Sciences Corp. (Nasdaq: EXAS) and OncoMethylome Sciences S.A. (Brussels: ONCOB) today announced that they have entered into a license agreement under which Exact Sciences has obtained exclusive, worldwide rights to up to (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Merck today announced a non-exclusive license agreement with Laboratory Corporation of America Holdings (LabCorp) for the commercialization of a genetic test that may help predict the response of patients with Hepatitis C virus (HCV) (…)
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[Source: Business Wire]
WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-At their meeting today, the Board of Directors of Merck & Co., Inc. declared a quarterly dividend of $0.38 per share on the company s common stock for the fourth quarter of 2010. Payment will be made on Oct. 7, 2010 to common (…)
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[Source: Business Wire]
PARIS & WHITEHOUSE STATION, N.J.-(BUSINESS WIRE)-Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) and Merck & Co., Inc. (NYSE: MRK) announced today that Raul E. Kohan will be appointed Chief Executive Officer of their proposed Animal Health joint venture. Sanofi-aventis and Merck (…)
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[Source: Business Wire]
Novel tricyclic indole-3-carboxamides were synthesized as structurally restricted analogs of bicyclic indoles, and found to be potent CB1 cannabinoid receptor agonists. The CB1 agonist activity depended on the absolute configuration of the chiral center of the tricyclic ring. (…)
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[Source: NCBI PubMed]