News: Wyeth

03.09.2010 | Bionity.com: One Nucleus announces new directorIndustry expert to support life sciences membership group

03.09.2010 - One Nucleus announced the appointment of Dr Alan Palmer as a Director. Alan is co-founder and currently Chief Scientific Officer for MS Therapeutics Ltd and has 30 years experience in the biotechnology sector in roles spanning academia, research and industry. Alan (…)

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[Source: Bionity.com]

02.09.2010 | BioSpace: Cordis Corporation (JNJ)'s Stent Does Better Than Medtronic, Inc. (MDT)'s Stent in Study Presented at European Society of Cardiology 2010

STOCKHOLM, September 2, 2010 /PRNewswire/ - Additional Analysis of 18 Month Data of the SORT OUT III Trial Provides Detail on Safety and Efficacy Outcomes in Patients With Diabetes, Acute Coronary Syndrome, or Treatment of Multiple Lesions. Three new analyses of subgroups from (…)

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[Source: BioSpace]

31.08.2010 | Business Wire: Research and Markets: Philippines Pharmaceuticals and Healthcare Report Q4 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/66a1b1/philippines_pharma) has announced the addition of the "Philippines Pharmaceuticals and Healthcare Report Q4 2010" report to their offering. Philippines Pharmaceuticals and (…)

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[Source: Business Wire]

31.08.2010 | Business Wire: Progenics Pharmaceuticals to Present Preclinical Study of Novel Monoclonal Antibodies Against C. difficile at 2010 ICAAC | Business Wire

TARRYTOWN, N.Y.-(BUSINESS WIRE)-Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) announced today that the Company will present preclinical findings for its humanized monoclonal antibodies that bind and neutralize the potentially life-threatening toxins produced by the (…)

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[Source: Business Wire]

30.08.2010 | Business Wire: Elan Corporation plc Announces Commencement of Asset Sale Offer to Purchase up to $186,000,000 of 8 7/8% Senior Fixed Rate Notes Due 2013 and Floating Rate Notes Due 2013 | Business Wire

DUBLIN-(BUSINESS WIRE)-Elan Corporation, plc ( œElan ) (NYSE: ELN) announced today that Elan s wholly-owned subsidiaries, Elan Finance public limited company ( œElan Finance ) and Elan Finance Corp. ( œElan Corp  and together with Elan Finance, the œIssuers ), (…)

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[Source: Business Wire]

30.08.2010 | BioSpace: ImmunoSolv Merges with Grampian BioConsultants & Secures Additional Funds

London - ImmunoSolv, a leading Edinburgh-based private company developer of immunology platform technology, is pleased to announce that it has completed a merger with Aberdeen-based Grampian BioConsultants Limited ( œGBC ). The merged company will retain the name ImmunoSolv (…)

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[Source: BioSpace]

25.08.2010 | NCBI PubMed: Course of dermal ulcers and musculoskeletal involvement in systemic sclerosis patients in the scleroderma lung study.

OBJECTIVE.: To evaluate changes in vascular and musculoskeletal involvement in subjects in the Scleroderma Lung Study (SLS), a multicenter, double-blind, randomized, controlled trial comparing placebo treatment to oral cyclophosphamide for 1 year in systemic sclerosis (SSc) (…)

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[Source: NCBI PubMed]

01.01.2010 | NCBI PubMed: Should animals navigating over short distances switch to a magnetic compass sense?

Magnetoreception can play a substantial role in long distance navigation by animals. I hypothesize that locomotion guided by a magnetic compass sense could also play a role in short distance navigation. Animals identify mates, prey, or other short distance navigational goals (…)

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[Source: NCBI PubMed]

26.08.2010 | Business Wire: Research and Markets: Best Practices in Working with Patient Advocacy Groups: Building Effective Relationships | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/360241/best_practices_in) has announced the addition of the "Best Practices in Working with Patient Advocacy Groups: Building Effective Relationships" report to their offering. Best (…)

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[Source: Business Wire]

01.10.2010 | NCBI PubMed: Asymmetry effect of particle size distribution on content uniformity and over-potency risk in low-dose solid drugs.

Most active pharmaceutical ingredients (API) exhibit particle size distributions with some degrees of asymmetry deviating from log-normality. A new log-skew-normal (L-S-N) distribution model is proposed for a systematic comparison of the asymmetry effect on content uniformity. (…)

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[Source: NCBI PubMed]

25.08.2010 | Business Wire: Research and Markets: Educating the Market: Creating Value Through Support of Continuing Medical Education 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/e9e8b4/educating_the_mark) has announced the addition of the "Educating the Market: Creating Value Through Support of Continuing Medical Education 2010" report to their offering. Educating (…)

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[Source: Business Wire]

25.08.2010 | Business Wire: Research and Markets: Pharmaceutical New Product Planning: Structure and Activities to Drive Growth and Profitability 2010 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/b5aaab/pharmaceutical_new) has announced the addition of the "Pharmaceutical New Product Planning: Structure and Activities to Drive Growth and Profitability 2010" report to their (…)

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[Source: Business Wire]

25.08.2010 | Business Wire: Research and Markets: Raising Disease State Awareness: Best Practices in Internal Brand Messaging for New Products | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/81e154/raising_disease_st) has announced the addition of the "Raising Disease State Awareness: Best Practices in Internal Brand Messaging for New Products" report to their offering. (…)

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[Source: Business Wire]

23.08.2010 | NCBI PubMed: Immunogenicity and Safety of 13-Valent Pneumococcal Conjugate Vaccine in Infants and Toddlers.

Background: 7-Valent pneumococcal conjugate vaccine (PCV7 [Prevnar, Wyeth Pharmaceuticals Inc, Philadelphia, PA], serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F) is effective in preventing vaccine-serotype pneumococcal disease. 13-Valent pneumococcal conjugate vaccine (PCV13) (PCV7 (…)

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[Source: NCBI PubMed]

24.08.2010 | Business Wire: Pharmaceutical Industry Executive Dr. Sidney Mazel Joins PRTM as Executive Vice President | Business Wire

WASHINGTON-(BUSINESS WIRE)-Dr. Sidney Mazel joins global management consulting firm PRTM as executive vice president of transaction services for the health care business group. In this role, he will manage PRTM s acquisition, divestiture and integration services for the firm (…)

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[Source: Business Wire]

19.08.2010 | NCBI PubMed: Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys.

Despite the eradication of smallpox, there is heightened concern that it could be reintroduced as a result of intentional release of Variola major virus through an act of bioterrorism. The live vaccine that was pivotal in the eradication of smallpox though considered a gold (…)

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[Source: NCBI PubMed]

23.08.2010 | BioSpace: HemoShear, LLC Appoints Leading Industry Executives to its Scientific Advisory Board

CHARLOTTESVILLE, Virginia, August 23, 2010/- HemoShear LLC today announced the appointments of Robert Ruffolo, Jr., Ph.D., former President of Research and Development for Wyeth Pharmaceuticals, and Kenneth Batchelor, Ph.D., former Senior Vice President for Drug Discovery with (…)

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[Source: BioSpace]

01.08.2010 | NCBI PubMed: Lessons from the salk polio vaccine: methods for and risks of rapid translation.

The Salk inactivated poliovirus vaccine is one of the most rapid examples of bench-to-bedside translation in medicine. In the span of 6 years, the key basic lab discoveries facilitating the development of the vaccine were made, optimization and safety testing was completed in (…)

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[Source: NCBI PubMed]

19.08.2010 | Business Wire: Research and Markets: OTC Healthcare in the US to 2014 | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/22ca66/otc_healthcare_in) has announced the addition of the "OTC Healthcare in the US to 2014" report to their offering. OTC Healthcare in the US to 2014 This databook provides key data (…)

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[Source: Business Wire]

19.08.2010 | NCBI PubMed: A cell-based screen for inhibitors of protein folding and degradation.

Cancer cells are exposed to external and internal stresses by virtue of their unrestrained growth, hostile microenvironment, and increased mutation rate. These stresses impose a burden on protein folding and degradation pathways and suggest a route for therapeutic intervention (…)

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[Source: NCBI PubMed]

13.08.2010 | NCBI PubMed: Inflammatory Cytokine and Chemokine Expression Is Differentially Modulated Acutely in the Dorsal Root Ganglion in Response to Different Nerve Root Compressions.

STUDY DESIGN.: Inflammatory proteins were quantified in bilateral dorsal root ganglions (DRGs) at 1 hour and 1 day using a multiplexed assay after 2 different unilateral nerve root compression injuries. OBJECTIVE.: To quantify cytokines and a chemokine in the DRG after nerve (…)

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[Source: NCBI PubMed]

17.08.2010 | Marketwire: Crucell Reports Record Revenues in Second Quarter 2010

LEIDEN, NETHERLANDS-(Marketwire - August 17, 2010) - PRESS RELEASE Crucell Reports Record Revenues in Second Quarter 2010 Total revenues and other operating income of EUR128.6 million, a 63% growth compared to the same period in 2009 (EUR78.7 million). Strong sales of (…)

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[Source: Marketwire]

17.08.2010 | Medical News Today: Antidepressant Helps Depression In Menopause

An antidepressant can alleviate symptoms of major depression in women experiencing or about to experience menopause, according to a study released today led by a Virginia Commonwealth University researcher. The research compared the effectiveness and safety of the (…)

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[Source: Medical News Today]

17.08.2010 | Business Wire: Research and Markets: Genzyme Corporation: Pharmavitae Profile | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/11e326/genzyme_corporatio) has announced the addition of the "Genzyme Corporation: PharmaVitae Profile" company profile to their offering. This analysis examines the historical and (…)

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[Source: Business Wire]

17.08.2010 | Business Wire: Research and Markets: Bristol-Myers Squibb Co.: PharmaVitae Profile | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/89d247/bristolmyers_squi) has announced the addition of the "Bristol-Myers Squibb Co.: PharmaVitae Profile" company profile to their offering. This analysis examines the historical and (…)

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[Source: Business Wire]

16.08.2010 | ScienceDaily: Antidepressant Can Help Treat Major Depression During Perimenopause, Menopause, Study Shows

ScienceDaily (Aug. 16, 2010) An antidepressant can alleviate symptoms of major depression in women experiencing or about to experience menopause, according to a study led by a Virginia Commonwealth University researcher. See Also: Health & Medicine Menopause Mental Health (…)

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[Source: ScienceDaily]

16.08.2010 | Business Wire: Inovio Pharmaceuticals Reports Second Quarter 2010 Financial Results | Business Wire

BLUE BELL, Pa.-(BUSINESS WIRE)-Inovio Pharmaceuticals, Inc. (NYSE AMEX: INO) today reported financial results for the quarter ended June 30, 2010. Total revenue was $1.1 million and $2.5 million for the three and six months ended June 30, 2010, compared to $2.5 million and (…)

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[Source: Business Wire]

16.08.2010 | Business Wire: Worldwide Clinical Trials Appoints Evelyn Graham as Executive Vice President, Global Business Development | Business Wire

KING OF PRUSSIA, Pa.-(BUSINESS WIRE)-Worldwide Clinical Trials, Inc., a privately held global contract research organization, today announced that Evelyn Graham has joined the company as Executive Vice President, Global Business Development. With more than 20 years of drug (…)

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[Source: Business Wire]

16.08.2010 | BioSpace: Former Solvay Pharmaceuticals, Inc. Chief Werner Cautreels, Ph.D. Takes Lead Role at Startup Selecta Biosciences, Inc.

WATERTOWN, Mass.-(BUSINESS WIRE)-Selecta Biosciences, Inc., a biopharmaceutical company developing synthetic nanoparticle vaccines and immunotherapies, announced today that Werner Cautreels, Ph.D. has been appointed as President and Chief Executive Officer. He has also been (…)

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[Source: BioSpace]

16.08.2010 | BioSpace: Inovio Pharmaceuticals (Formerly Known as Inovio Biomedical Corporation) (INO) Reports Second Quarter 2010 Financial Results

BLUE BELL, PA August 16, 2010 Inovio Pharmaceuticals, Inc. (NYSE AMEX: INO) today reported financial results for the quarter ended June 30, 2010. Total revenue was $1.1 million and $2.5 million for the three and six months ended June 30, 2010, compared to $2.5 million and $2.9 (…)

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[Source: BioSpace]

01.02.2005 | NCBI PubMed: Actively immunizing patients with HIV-1: Progress on the development of a therapeutic vaccine.

Extract: Despite more than twenty years of research relating to HIV-1, human immunodeficiency virus type-1, HIV-1 infection remains a public health threat of extraordinary proportions. The World Health Organization estimates that in the year 2003 alone, 4.8 million people were (…)

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[Source: NCBI PubMed]

01.04.2005 | NCBI PubMed: Rediscovering natural products as a source of new drugs.

Extract: Since the very beginnings of human medicine, physicians have relied on chemical compounds produced by animals, plants and microorganisms, so-called natural products, to treat diseases. Natural products are directly or indirectly responsible for roughly one-half of all (…)

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[Source: NCBI PubMed]

01.09.2010 | NCBI PubMed: Effect of oral contraceptives on markers of hyperandrogenism and SHBG in women with polycystic ovary syndrome.

BACKGROUND: This randomized study's aim was to compare the effect of four oral contraceptives (OCs) containing 30 mcg of ethinylestradiol (EE) and different progestogens [drospirenone, (DRSP), chlormadinone acetate (CMA), desogestrel (DSG), gestodene (GSD)] on biochemical and (…)

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[Source: NCBI PubMed]

10.08.2010 | NCBI PubMed: Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study.

BACKGROUND: Gram-negative Enterobacteriaceae with resistance to carbapenem conferred by New Delhi metallo-beta-lactamase 1 (NDM-1) are potentially a major global health problem. We investigated the prevalence of NDM-1, in multidrug-resistant Enterobacteriaceae in India, (…)

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[Source: NCBI PubMed]

13.08.2010 | Business Wire: Research and Markets: Stakeholder Opinions: Vaccines in Emerging Markets (Latin America) - Opportunities in Brazil, Mexico and Argentina | Business Wire

DUBLIN-(BUSINESS WIRE)-Research and Markets (http:/www.researchandmarkets.com/research/affcf7/stakeholder_opinio) has announced the addition of the "Stakeholder Opinions: Vaccines in Emerging Markets (Latin America) - Opportunities in Brazil, Mexico and Argentina" report to (…)

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[Source: Business Wire]

12.08.2010 | Medical News Today: Linking Superbug To India "Is Totally Irrational" Say Indian Authorities

Indian authorities say it is unfair to associate the superbug that has surfaced in Great Britain to India, because a significant number of bacteria carrying the NDM-1 gene (DNA code) have been reported in several different countries, including Brazil, the USA, Canada, Puerto (…)

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[Source: Medical News Today]

11.08.2010 | Marketwire: Crucell and Harvard (BIDMC) Join Forces with IAVI to Advance AdVac-based AIDS Vaccine

LEIDEN, NETHERLANDS-(Marketwire - August 11, 2010) - Dutch biopharmaceutical company Crucell N.V. (NYSE Euronext, NASDAQ: CRXL) (SWISS: CRX) today announces its intention to participate in an international Phase I clinical trial in the United States and Africa of a combination (…)

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[Source: Marketwire]

11.08.2010 | BioSpace: Crucell N.V. (CRXL) to Release Second Quarter 2010 Results on Tuesday August 17, 2010

LEIDEN, NETHERLANDS-(Marketwire - August 11, 2010) - Dutch biopharmaceutical company Crucell N.V. (NYSE Euronext, NASDAQ: CRXL) (SWISS: CRX) today announced that it will release its financial results for the second quarter 2010 on Tuesday August 17, 2010 at 07:45 AM Central (…)

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[Source: BioSpace]

10.08.2010 | Business Wire: CorMedix Announces Appointment of Key Positions | Business Wire

BRIDGEWATER, N.J.-(BUSINESS WIRE)-CorMedix Inc. ( œCorMedix ) (NYSE Amex: CRMD), a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of Cardiorenal disease, today announced the appointment of Robert D. (…)

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[Source: Business Wire]

01.01.2010 | NCBI PubMed: Beyond symptomatic improvement:assessing real-world outcomes in patients with major depressive disorder.

OBJECTIVE: To quantify the negative impact that major depressive disorder (MDD) has on quality of life, disability, and work, family, and overall psychosocial functioning. Available scales that assess these areas of impairment as they relate to patients with MDD are described. (…)

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[Source: NCBI PubMed]

01.08.2010 | NCBI PubMed: Bipolar disorder and pregnancy: maintaining psychiatric stability in the real world of obstetric and psychiatric complications.

Am J Psychiatry. |-| Burt VK, Bernstein C, Rosenstein WS, Altshuler LL. |-| Dr. Burt has served as consultant or adviser to, or on the speakers bureau of, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Noven Pharmaceuticals, Takeda Pharmaceuticals, and Wyeth-Ayerst. Dr. (…)

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[Source: NCBI PubMed]

01.01.2009 | NCBI PubMed: GPC Spin Column HPLC-ESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins.

Secondary drug screening methods are described for determining the relative degree of non-covalent binding between drug candidates and a protein of therapeutic interest by gel centrifugation chromatography using GPC spin columns for isolating the protein-drug complexes, under (…)

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[Source: NCBI PubMed]